Browsing by Subject "Vitamin E"
Now showing items 1-7 of 7
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Article
D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells
(2014)d-alpha-tocopheryl polyethylene glycol succinate (TPGS) is a vitamin E derivative that has been intensively applied as a vehicle for drug delivery systems to enhance drug solubility and increase the oral bioavailability ...
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Article
Drug delivery innovations for enhancing the anticancer potential of vitamin e isoforms and their derivatives
(2015)Vitamin E isoforms have been extensively studied for their anticancer properties. Novel drug delivery systems (DDS) that include liposomes, nanoparticles, and micelles are actively being developed to improve Vitamin E ...
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Article
Induction of caspase-independent programmed cell death by vitamin E natural homologs and synthetic derivatives.
(2009)Current observations in the literature suggest that vitamin E may be a suitable candidate for cancer chemotherapy. To investigate this further, we examined the ability of the vitamin E natural homologs [alpha-, beta-, ...
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Article
Induction of DNA damage and caspase-independent programmed cell death by vitamin e
(2012)Vitamin E comprises 8 functionally unique isoforms and may be a suitable candidate for the adjuvant treatment of prostate cancer. In this study, we examined the ability of 2 vitamin E isoforms [α-tocotrienol (γ-TT) and ...
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Article
Synthesis and study of the cancer cell growth inhibitory properties of α-, γ-tocopheryl and γ-tocotrienyl 2-phenylselenyl succinates
(2006)Vitamin E succinate selenium-conjugated molecules were synthesized and their apoptogenic properties were evaluated. 4-Methyl-2-phenylselenyl succinate (4) was prepared by the reaction of sodium benzeneselenolate with ...
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Article
Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogs
(2008)Current observations in the literature suggest that vitamin E may be a suitable candidate for the adjuvant treatment of cancer. Even though historically most research focused on α-tocopherol, more recent evidence suggests ...
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Doctoral Thesis Open Access
Βιολογικά ενεργές, μεικτές, διφωσφονικές και φθορίζουσες καρβοξυλικές ενώσεις με συστατικά της βιταμίνης Ε
(Πανεπιστήμιο Κύπρου, Σχολή Κοινωνικών Επιστημών και Επιστημών Αγωγής / University of Cyprus, Faculty of Social Sciences and Education, 2014-05)Τα τελευταία χρόνια οι μεικτές ενώσεις της τοκοφερόλης με δικαρβοξυλικά οξέα παρουσιάζουν ιδιαίτερο ενδιαφέρον λόγο της αποπτωτικής / αντικαρκινικής τους δράσης. Στην παρούσα διατριβή συντέθηκαν και χαρακτηρίστηκαν νέες ...